Tg(Col1a1-cre/Esr1*)1Mis
Transgene Detail

Summary

• Symbol: Tg(Col1a1-cre/Esr1*)1Mis
• Name: transgene insertion 1, Yuji Mishina
• MGI ID: MGI:3829219
• Synonyms: Col1-CreER^TM, Tg(Col1a1-cre/ERT2)1Mis
• Transgene: Tg(Col1a1-cre/Esr1*)1Mis Location: unknown
• Alliance: Tg(Col1a1-cre/Esr1*)1Mis page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Col1a1-cre/Esr1*)1Mis expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Col1a1

• Mutation details: The promoter was used to drive expression of an inducible cre/ERT2 (ESR1) fusion in osteoblasts, odontoblasts and tendon fibroblasts. No line information is available. (J:143588)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Col1a1 (species not specified) Summary of all recombinase alleles driven by Col1a1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:143588 Kamiya N, et al., BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11
• All: 8 reference(s)