Tg(THY1-APOD1)1Era
Transgene Detail

Summary

• Symbol: Tg(THY1-APOD1)1Era
• Name: transgene insertion 1, Eric Rassart
• MGI ID: MGI:3829246
• Synonyms: H-apoD Tg, HApoD-Tg
• Transgene: Tg(THY1-APOD1)1Era Location: unknown
• Alliance: Tg(THY1-APOD1)1Era page

Transgene origin

• Strain of Origin: (CBA x C57BL/6)

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(THY1-APOD1)1Era expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  APOD (347)

  Apod	(MGI:88056)

• Mutation details: This transgene consists of a 3.5 kb fragment of the human THY1 promoter/enhancer region, a 0.7 kb cDNA encoding the human APOD gene, and a 0.2 kb fragment encoding the bovine growth hormone consensus polyadenylation signal. Northern blot analysis indicates strong expression in the central nervous system and weaker expression in the thymus and heart. (J:143809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:143809 Ganfornina MD, et al., Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress. Aging Cell. 2008 Aug;7(4):506-15
• All: 4 reference(s)