Lrig3^tm1.1Good
Targeted Allele Detail

Summary

• Symbol: Lrig3^tm1.1Good
• Name: leucine-rich repeats and immunoglobulin-like domains 3; targeted mutation 1.1, Lisa Goodrich
• MGI ID: MGI:3829388
• Gene: Lrig3 Location: Chr10:125802088-125851228 bp, + strand Genetic Position: Chr10, 73.66 cM, cytoband D3
• Alliance: Lrig3^tm1.1Good page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:142510
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre-mediated recombination was used to remove exon 1. The absence of transcript expression was confirmed (data not shown). (J:142510)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrig3 Mutation: 64 strains or lines available

References

• Original: J:142510 Abraira VE, et al., Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear. Development. 2008 Dec;135(24):4091-9
• All: 2 reference(s)