Flcn^tm1.1Btt
Targeted Allele Detail

Summary

• Symbol: Flcn^tm1.1Btt
• Name: folliculin; targeted mutation 1.1, Bin Tean Teh
• MGI ID: MGI:3829644
• Synonyms: BHD^-
• Gene: Flcn Location: Chr11:59682234-59700842 bp, - strand Genetic Position: Chr11, 37.79 cM
• Alliance: Flcn^tm1.1Btt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143922
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination of Flcn^tm1Btt removed exons 3 and 4. (J:143922)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Flcn Mutation: 42 strains or lines available

References

• Original: J:143922 Chen J, et al., Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia. PLoS One. 2008;3(10):e3581
• All: 1 reference(s)