Xist^tm5Sado
Targeted Allele Detail

Summary

• Symbol: Xist^tm5Sado
• Name: inactive X specific transcripts; targeted mutation 5, Takashi Sado
• MGI ID: MGI:3829654
• Synonyms: Xist^deltaA
• Gene: Xist Location: ChrX:102503979-102526839 bp, - strand Genetic Position: ChrX, 46.15 cM, cytoband D
• Alliance: Xist^tm5Sado page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:142921
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The portion of exon 1 encoding the A repeat was replaced with a neo cassette. Germ line, cre-mediated recombination was used to remove the neo cassette. (J:142921)

Expression

In Mice Carrying this Mutation:	3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Xist Mutation: 8 strains or lines available

References

• Original: J:142921 Hoki Y, et al., A proximal conserved repeat in the Xist gene is essential as a genomic element for X-inactivation in mouse. Development. 2009 Jan;136(1):139-46
• All: 12 reference(s)