Rptor^tm1.1Rueg
Targeted Allele Detail

Summary

• Symbol: Rptor^tm1.1Rueg
• Name: regulatory associated protein of MTOR, complex 1; targeted mutation 1.1 Markus A Reugg
• MGI ID: MGI:3829706
• Synonyms: raptor^-
• Gene: Rptor Location: Chr11:119493731-119790402 bp, + strand Genetic Position: Chr11, 83.96 cM, cytoband E2
• Alliance: Rptor^tm1.1Rueg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143749
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Germ line cre-mediated reombination was used to remove exon 6. (J:143749)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rptor Mutation: 117 strains or lines available

References

• Original: J:143749 Polak P, et al., Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration. Cell Metab. 2008 Nov;8(5):399-410
• All: 1 reference(s)