Tg(CA2-cre/Esr1*)1Subw
Transgene Detail

Summary

• Symbol: Tg(CA2-cre/Esr1*)1Subw
• Name: transgene insertion 1, Susan Bonner-Weir
• MGI ID: MGI:3829880
• Synonyms: CAII-CreER^TM, Tg(CA2-cre/ERT)1Subw
• Transgene: Tg(CA2-cre/Esr1*)1Subw Location: unknown
• Alliance: Tg(CA2-cre/Esr1*)1Subw page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(CA2-cre/Esr1*)1Subw expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  CA2 (760)

  Car2	(MGI:88269)

• Mutation details: The human promoter was used to drive inducible expression in pancreatic ductal cells. No line information is available. (J:142917)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CA2 (human) Summary of all recombinase alleles driven by CA2. Comparative matrix view of recombinase activities Alliance human CA2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:142917 Inada A, et al., Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19915-9
• All: 3 reference(s)