Crk^tm1Cur
Targeted Allele Detail

Summary

• Symbol: Crk^tm1Cur
• Name: v-crk avian sarcoma virus CT10 oncogene homolog; targeted mutation 1, Tom Curran
• MGI ID: MGI:3830007
• Synonyms: Crk^f
• Gene: Crk Location: Chr11:75570085-75597734 bp, + strand Genetic Position: Chr11, 45.92 cM, cytoband A-D
• Alliance: Crk^tm1Cur page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143049
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A single loxP site was inserted 5' to exon 1, and a loxP-flanked neomycin selection cassete was inserted 3' to exon 1. (J:111399)

Expression

In Mice Carrying this Mutation:	183 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crk Mutation: 21 strains or lines available

References

• Original: J:143049 Park TJ, et al., Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway. J Neurosci. 2008 Dec 10;28(50):13551-62
• All: 10 reference(s)