Erap1^tm1.1Gnie
Targeted Allele Detail

Summary

• Symbol: Erap1^tm1.1Gnie
• Name: endoplasmic reticulum aminopeptidase 1; targeted mutation 1.1, Gabriele Niedermann
• MGI ID: MGI:3830089
• Gene: Erap1 Location: Chr13:74787692-74841321 bp, + strand Genetic Position: Chr13, 40.48 cM, cytoband C1
• Alliance: Erap1^tm1.1Gnie page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143988
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 4 was removed by germ line, cre-mediated recombination. The expression of transcripts lacking exon 4 was confirmed by RT-PCR on spleen extracts. (J:143988)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Erap1 Mutation: 59 strains or lines available

References

• Original: J:143988 Firat E, et al., The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation. J Immunol. 2007 Feb 15;178(4):2241-8
• All: 1 reference(s)