Eppk1^tm1Safu
Targeted Allele Detail

Summary

• Symbol: Eppk1^tm1Safu
• Name: epiplakin 1; targeted mutation 1, Sakuhei Fujiwara
• MGI ID: MGI:3830327
• Synonyms: EPPK^-
• Gene: Eppk1 Location: Chr15:75973337-76004395 bp, - strand Genetic Position: Chr15, 35.37 cM
• Alliance: Eppk1^tm1Safu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144147
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A beta-geo cassette was inserted into exon 2. The absence of wild-type transcript expression was confirmed by RT-PCR on skin extracts. (J:144147)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eppk1 Mutation: 39 strains or lines available

References

• Original: J:144147 Goto M, et al., Elimination of epiplakin by gene targeting results in acceleration of keratinocyte migration in mice. Mol Cell Biol. 2006 Jan;26(2):548-58
• All: 2 reference(s)