Tg(Dct-Birc5)21Gros
Transgene Detail
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| Symbol: |
Tg(Dct-Birc5)21Gros |
| Name: |
transgene insertion 21, Doug Grossman |
| MGI ID: |
MGI:3830337 |
| Synonyms: |
Dct-Survivin |
| Transgene: |
Tg(Dct-Birc5)21Gros Location: unknown
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| Alliance: |
Tg(Dct-Birc5)21Gros page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Dct-Birc5)21Gros expresses
1 gene
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Mutation details: A transgenic construct containing the mouse Birc5 (baculoviral IAP repeat-containing 5) gene under the control of the mouse Dct, dopachrome tautomerase, promoter and 0.8 kb of SV40 polyadenylation sequences was injected into fertilized (C57BL/6 x CBA)F1 mouse eggs. Founder line 21 was subsequently established. Expression is detectable in hair follicle melanocytes by in situ hybridization.
(J:122181)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:122181 Thomas J, et al., Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice. Cancer Res. 2007 Jun 1;67(11):5172-8 |
| All: |
1 reference(s) |
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Analysis Tools
