Qrfpr^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Qrfpr^tm1Lex
• Name: pyroglutamylated RFamide peptide receptor; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3830475
• Gene: Qrfpr Location: Chr3:36233575-36276462 bp, - strand Genetic Position: Chr3, 17.41 cM
• Alliance: Qrfpr^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144011
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• All of exon 1 was replaced with a lacZ neo cassette via homologous recombination. (J:144011)

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Qrfpr Mutation: 33 strains or lines available

References

• Original: J:144011 Baribault H, et al., The G-protein-coupled receptor GPR103 regulates bone formation. Mol Cell Biol. 2006 Jan;26(2):709-17
• All: 1 reference(s)