Rhoh^tm1Hasu
Targeted Allele Detail

Summary

• Symbol: Rhoh^tm1Hasu
• Name: ras homolog family member H; targeted mutation 1, Harumi Suzuki
• MGI ID: MGI:3830828
• Gene: Rhoh Location: Chr5:66018556-66054043 bp, + strand Genetic Position: Chr5, 33.8 cM, cytoband D
• Alliance: Rhoh^tm1Hasu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143491
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The coding region in exon 3 was replaced with a lacZ/neo cassette. (J:143491)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rhoh Mutation: 13 strains or lines available

References

• Original: J:143491 Oda H, et al., RhoH plays critical roles in FcepsilonRI-dependent signal transduction in mast cells. J Immunol. 2009 Jan 15;182(2):957-62
• All: 3 reference(s)