Mro^tm1H
Targeted Allele Detail

Summary

• Symbol: Mro^tm1H
• Name: maestro; targeted mutation 1, Harwell
• MGI ID: MGI:3831006
• Gene: Mro Location: Chr18:73992465-74014405 bp, + strand Genetic Position: Chr18, 50.21 cM, cytoband E2
• Alliance: Mro^tm1H page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144349
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 5 through 9, which contain the 4 heat domains, were replaced with a lacZ and neo cassette. The absence of transcript expression was confirmed by RT-PCR on male embryonic gonad extracts. (J:144349)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Mro Mutation: 19 strains or lines available

Notes

ES cell line = 48/1

References

• Original: J:144349 Smith L, et al., The Maestro (Mro) gene is dispensable for normal sexual development and fertility in mice. PLoS One. 2008;3(12):e4091
• All: 2 reference(s)