Gtf2i^Gt(XC455)Byg
Gene trapped Allele Detail

Summary

• Symbol: Gtf2i^Gt(XC455)Byg
• Name: general transcription factor II I; gene trap XC455, BayGenomics
• MGI ID: MGI:3831531
• Gene: Gtf2i Location: Chr5:134266688-134343614 bp, - strand Genetic Position: Chr5, 74.48 cM
• Alliance: Gtf2i^Gt(XC455)Byg page

Mutation origin

• Mutant Cell Line: XC455
• Germline Transmission: Earliest citation of germline transmission: J:143508
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: A gene trap vector pGT1Lxf containing beta-geo was inserted into intron 9 upstream of the functional nuclear localization signal. (J:143508)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XC455	CC178407 ; (MGI Seq Detail)	5' RACE	Chr5:134308292-134322641 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  124 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gtf2i Mutation: 139 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:143508 Enkhmandakh B, et al., Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):181-6
• All: 2 reference(s)