Plxna1^tm2Tmj
Targeted Allele Detail

Summary

• Symbol: Plxna1^tm2Tmj
• Name: plexin A1; targeted mutation 2, Thomas M Jessell
• MGI ID: MGI:3831875
• Gene: Plxna1 Location: Chr6:89293295-89339595 bp, - strand Genetic Position: Chr6, 39.91 cM, cytoband E2
• Alliance: Plxna1^tm2Tmj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144660
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2, and a floxed neo cassette was inserted downstream of exon 2. (J:144660)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxna1 Mutation: 75 strains or lines available

References

• Original: J:144660 Yoshida Y, et al., PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Neuron. 2006 Dec 7;52(5):775-88
• All: 4 reference(s)