Tg(CAG-Bgeo,-Fgf4)1Mrt
Transgene Detail

Summary

• Symbol: Tg(CAG-Bgeo,-Fgf4)1Mrt
• Name: transgene insertion 1, Gail Martin
• MGI ID: MGI:3832033
• Synonyms: Fgf4^GOF
• Transgene: Tg(CAG-Bgeo,-Fgf4)1Mrt Location: unknown
• Alliance: Tg(CAG-Bgeo,-Fgf4)1Mrt page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:104411
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Bgeo,-Fgf4)1Mrt expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fgf4 (MGI:95518)

• Mutation details: A floxed beta-geo was fused to a complete CDNA of mouse Fgf4 and placed under the control of the CAG promoter. (J:104411)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:104411 Lu P, et al., Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function. Development. 2006 Jan;133(1):33-42
• All: 1 reference(s)