Tg(SMN2)46Tro
Transgene Detail

Summary

• Symbol: Tg(SMN2)46Tro
• Name: transgene insertion 46, Thierry Bordet
• MGI ID: MGI:3832058
• Synonyms: SMN2(N46)
• Transgene: Tg(SMN2)46Tro Location: unknown
• Alliance: Tg(SMN2)46Tro page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(SMN2)46Tro expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SMN2 (6607)

  Smn1	(MGI:109257)

• Mutation details: A 35.5 kb Ba mHI genomic fragment encoding the human SMN2 promoter and gene (derived from genomic clone PAC215P15) was injected into fertilized FVB/N mouse oocytes. Transgenic SMN2 mice from founder line 46, which contains 2 copies of the transgene, were established. (J:144853)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:144853 Bordet T, Generation of an SMN2 transgene (line 46). MGI Direct Data Submission. 2009
• All: 2 reference(s)