Tg(Scgb1a1-STAT6)1Erle
Transgene Detail

Summary

• Symbol: Tg(Scgb1a1-STAT6)1Erle
• Name: transgene insertion 1, David J Erle
• MGI ID: MGI:3832263
• Synonyms: Epi-hSTAT6
• Transgene: Tg(Scgb1a1-STAT6)1Erle Location: unknown
• Alliance: Tg(Scgb1a1-STAT6)1Erle page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Scgb1a1-STAT6)1Erle expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  STAT6 (6778)

  Stat6

  (MGI:103034)

• Mutation details: Expresion of a full length human STAT6 cDNA was place under the control of the rat Scgb1a1 promoter. Human growth hormone intronic and polyadenalation sequence was placed 3' to the STAT6 cDNA. (J:132385)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:132385 Kuperman DA, et al., Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med. 2002 Aug;8(8):885-9
• All: 1 reference(s)