Tg(SFTPC-ITGB6)1Des
Transgene Detail

Summary

• Symbol: Tg(SFTPC-ITGB6)1Des
• Name: transgene insertion 1, Dean Sheppard
• MGI ID: MGI:3832271
• Transgene: Tg(SFTPC-ITGB6)1Des Location: unknown
• Alliance: Tg(SFTPC-ITGB6)1Des page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(SFTPC-ITGB6)1Des expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ITGB6 (3694)

  Itgb6

  (MGI:96615)

• Mutation details: Expression of a full length human ITGB6 cDNA was placed under the control of the human SFTPC promoter. The small t intron and polyadenylation sequence from SV40 were place 3' to the ITGB6 cDNA. (J:51592)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:51592 Huang X, et al., Expression of the human integrin beta6 subunit in alveolar type II cells and bronchiolar epithelial cells reverses lung inflammation in beta6 knockout mice. Am J Respir Cell Mol Biol. 1998 Oct;19(4):636-42
• All: 1 reference(s)