T(1E2.1;8B1.2)2Lub
Spontaneous Allele Detail

Summary

• Symbol: T(1E2.1;8B1.2)2Lub
• Name: reciprocal translocation, Chr 1 and 8, Medizinische Hochschule Lubeck 2
• MGI ID: MGI:3832322
• Gene: T(1E2.1;8B1.2)2Lub Location: unknown Genetic Position: Chr1, Syntenic

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Translocation
• Mutation details: Position 101,775,857 of chromosome 1 is fused to position 33,249,461 of chromosome 8. One extra base, T, is found in between the fused ends. The breakpoint on chromosome 1 falls in the first intron of Cntnap5b. No known genes are located near the breakpoint in chromosome 8. RT-PCR confirms the absence of Cntnap5b expression in brains from homozygous mice. (J:144618)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any T(1E2.1;8B1.2)2Lub Mutation: 0 strains or lines available

References

• Original: J:144618 Weichenhan D, et al., A mouse translocation associated with Caspr5-2 disruption and perinatal lethality. Mamm Genome. 2008 Dec;19(10-12):675-86
• All: 1 reference(s)