Scnn1b^tm1.2Hum
Targeted Allele Detail

Summary

• Symbol: Scnn1b^tm1.2Hum
• Name: sodium channel, nonvoltage-gated 1 beta; targeted mutation 1.2, Edith Hummer
• MGI ID: MGI:3832671
• Synonyms: Scnn1b^deltaneo
• Gene: Scnn1b Location: Chr7:121464261-121517737 bp, + strand Genetic Position: Chr7, 65.07 cM
• Alliance: Scnn1b^tm1.2Hum page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144725
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Germ line, cre-mediated recombination was used to remove exon 2. The neo cassette was retained. (J:144725)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scnn1b Mutation: 49 strains or lines available

References

• Original: J:144725 Merillat AM, et al., Conditional gene targeting of the ENaC subunit genes Scnn1b and Scnn1g. Am J Physiol Renal Physiol. 2009 Feb;296(2):F249-56
• All: 1 reference(s)