Scnn1g^tm1.1Hum
Targeted Allele Detail

Summary

• Symbol: Scnn1g^tm1.1Hum
• Name: sodium channel, nonvoltage-gated 1 gamma; targeted mutation 1.1, Edith Hummer
• MGI ID: MGI:3832674
• Synonyms: Scnn1g^lox
• Gene: Scnn1g Location: Chr7:121333702-121367698 bp, + strand Genetic Position: Chr7, 65.07 cM
• Alliance: Scnn1g^tm1.1Hum page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144725
• Parent Cell Line: GS1 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2, and an additional loxP site was inserted downstream of exon 2. Germ line, flp-recombination was used to remove the neo cassette. (J:144725)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Scnn1g Mutation: 32 strains or lines available

References

• Original: J:144725 Merillat AM, et al., Conditional gene targeting of the ENaC subunit genes Scnn1b and Scnn1g. Am J Physiol Renal Physiol. 2009 Feb;296(2):F249-56
• All: 2 reference(s)