Tg(I12b-cre)1Jlr
Transgene Detail

Summary

• Symbol: Tg(I12b-cre)1Jlr
• Name: transgene insertion 1, John L R Rubenstein
• MGI ID: MGI:3833422
• Synonyms: Dlx1/2-cre, Dlx-Cre, Dlx I12b-Cre, Dlx-I12bCre, Tg(Rr293-cre)1Jlr
• Transgene: Tg(I12b-cre)1Jlr Location: unknown
• Alliance: Tg(I12b-cre)1Jlr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(I12b-cre)1Jlr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Rr293 (MGI:7356080)

• Mutation details: The I12b enhancer element of Dlx1/Dlx2 was placed upstreaam of the beta-globin minimal promoter and a cre recombinase having a nuclear localization signal. Four of 11 founders had single integration sites. (J:144850)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Rr293 (mouse) Summary of all recombinase alleles driven by Rr293. Comparative matrix view of recombinase activities Alliance mouse Rr293 gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:144850 Potter GB, et al., Generation of Cre-transgenic mice using Dlx1/Dlx2 enhancers and their characterization in GABAergic interneurons. Mol Cell Neurosci. 2009 Feb;40(2):167-86
• All: 21 reference(s)