Kif22^tm1.1Tya
Targeted Allele Detail

Summary

• Symbol: Kif22^tm1.1Tya
• Name: kinesin family member 22; targeted mutation 1.1, Tadashi Yamamoto
• MGI ID: MGI:3834595
• Synonyms: Kid^-
• Gene: Kif22 Location: Chr7:126626901-126641639 bp, - strand Genetic Position: Chr7, 69.29 cM
• Alliance: Kif22^tm1.1Tya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145315
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove the cDNA and exon 3. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts. (J:145315)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif22 Mutation: 34 strains or lines available

References

• Original: J:145315 Ohsugi M, et al., Kid-mediated chromosome compaction ensures proper nuclear envelope formation. Cell. 2008 Mar 7;132(5):771-82
• All: 1 reference(s)