Cngb1^tm1Hazh
Targeted Allele Detail

Summary

• Symbol: Cngb1^tm1Hazh
• Name: cyclic nucleotide gated channel beta 1; targeted mutation 1, Haiqing Zhao
• MGI ID: MGI:3834618
• Synonyms: CNBG1^deltaCaM
• Gene: Cngb1 Location: Chr8:95965673-96033213 bp, - strand Genetic Position: Chr8, 47.12 cM
• Alliance: Cngb1^tm1Hazh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145296
• Parent Cell Line: MC1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The sequence encoding the 20 amino acids of the calmodulin binding domain was removed, and a floxed neo cassette used for selection was removed by germ line, cre mediated recombination. (J:145296)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cngb1 Mutation: 61 strains or lines available

References

• Original: J:145296 Song Y, et al., Olfactory CNG channel desensitization by Ca2+/CaM via the B1b subunit affects response termination but not sensitivity to recurring stimulation. Neuron. 2008 May 8;58(3):374-86
• All: 2 reference(s)