Pirt^tm1Xzd
Targeted Allele Detail

Summary

• Symbol: Pirt^tm1Xzd
• Name: phosphoinositide-interacting regulator of transient receptor potential channels; targeted mutation 1, Xinzhong Dong
• MGI ID: MGI:3834636
• Synonyms: Pirt^-
• Gene: Pirt Location: Chr11:66802807-66820702 bp, + strand Genetic Position: Chr11, 40.59 cM
• Alliance: Pirt^tm1Xzd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145300
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced with a farnesylated EGFP, an IRES-reverse tetracylcine transactivatior (IRES-rtTA), and a self-excising neo cassette. (J:145300)

Expression

In Mice Carrying this Mutation:

20 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pirt Mutation: 13 strains or lines available

References

• Original: J:145300 Kim AY, et al., Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1. Cell. 2008 May 2;133(3):475-85
• All: 9 reference(s)