Tnfrsf9tm1Lpc
Targeted Allele Detail
|
|
| Symbol: |
Tnfrsf9tm1Lpc |
| Name: |
tumor necrosis factor receptor superfamily, member 9; targeted mutation 1, Lieping Chen |
| MGI ID: |
MGI:3834749 |
| Synonyms: |
CD137- |
| Gene: |
Tnfrsf9 Location: Chr4:151004612-151030561 bp, + strand Genetic Position: Chr4, 81.52 cM
|
| Alliance: |
Tnfrsf9tm1Lpc page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:145439
|
| Parent Cell Line: |
Not Specified (ES Cell)
|
| Strain of Origin: |
129/Sv
|
|
| Allele Type: |
|
Targeted (Null/knockout) |
| Mutations: |
|
Insertion, Intragenic deletion
|
| |
|
Mutation details: The signal peptide with the ATG translation initiation codon and the first 6 exons encoding the extracellular and transmembrane regions were replaced with a neo cassette. The absence of protein expression was confirmed by analysis of Con A-activated spleen cells.
(J:145439)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Tnfrsf9 Mutation: |
49 strains or lines available
|
|
| Original: |
J:145439 Zhu Y, et al., CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype. Blood. 2007 Jun 1;109(11):4882-9 |
| All: |
5 reference(s) |
|
Analysis Tools
