Tg(H2-Ea-Tnfsf9)16Lpc
Transgene Detail

Summary

• Symbol: Tg(H2-Ea-Tnfsf9)16Lpc
• Name: transgene insertion 16, Lieping Chen
• MGI ID: MGI:3834750
• Synonyms: 4-1BBL-Tg
• Transgene: Tg(H2-Ea-Tnfsf9)16Lpc Location: unknown
• Alliance: Tg(H2-Ea-Tnfsf9)16Lpc page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-Ea-Tnfsf9)16Lpc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tnfsf9 (MGI:1101058)

• Mutation details: The promoter was used to drive expression of the cDNA in MHC class II+ cells. The cDNA is preceded by an intron and followed by a polyadenylation sequence from the rabbit beta-globin gene. Two lines were created (lines 9 and 16) with line 16 selected as the representative line. (J:132372)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:132372 Zhu G, et al., Progressive depletion of peripheral B lymphocytes in 4-1BB (CD137) ligand/I-Ealpha)-transgenic mice. J Immunol. 2001 Sep 1;167(5):2671-6
• All: 2 reference(s)