Cldn6^tm1(cre)Dkwu
Targeted Allele Detail

Summary

• Symbol: Cldn6^tm1(cre)Dkwu
• Name: claudin 6; targeted mutation 1, Doris Wu
• MGI ID: MGI:3834897
• Synonyms: Claudin6-cre
• Gene: Cldn6 Location: Chr17:23898345-23901417 bp, + strand Genetic Position: Chr17, 11.99 cM
• Alliance: Cldn6^tm1(cre)Dkwu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145443
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Cldn6^tm1(cre)Dkwu expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cldn6 (MGI:1859284)

• Mutation details: A targeting vector was use to replace the only exon of the gene with an inserted cre coding sequence. (J:145443)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cldn6 (mouse) Summary of all recombinase alleles driven by Cldn6. Alliance mouse Cldn6 gene page

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cldn6 Mutation: 20 strains or lines available

References

• Original: J:145443 Wu D, Generation of a cre knock-in allele of Cldn6. MGI Direct Data Submission. 2009
• All: 2 reference(s)