Tg(TcraTcrbAD10)1Hed
Transgene Detail
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| Symbol: |
Tg(TcraTcrbAD10)1Hed |
| Name: |
transgene insertion 1, Stephen M Hedrick |
| MGI ID: |
MGI:3835444 |
| Synonyms: |
AD10 |
| Transgene: |
Tg(TcraTcrbAD10)1Hed Location: unknown
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| Alliance: |
Tg(TcraTcrbAD10)1Hed page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TcraTcrbAD10)1Hed expresses
2 genes
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Mutation details: Productively rearranged Tcra and Tcrb genes were cloned from the murine T cell clone AD10 that is specific for pigeon cytochrome-c. In mice expressing I-Ek, or I-Eb, greater than 90% of thymocytes and T cells express the transgenic TCR. The alpha-chain of this transgenic TCR differs by one amino acid (a threonine instead of an alanine at position 99) to the alpha chain of the transgenic TCR expressed in Tg(TcrAND)53Hed transgenic mice.
(J:124701)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:124701 Kaye J, et al., Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition. J Immunol. 1992 Jun 1;148(11):3342-53 |
| All: |
12 reference(s) |
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Analysis Tools
