Parvb^tm1Ref
Targeted Allele Detail

Summary

• Symbol: Parvb^tm1Ref
• Name: parvin, beta; targeted mutation 1, Reinhard Fassler
• MGI ID: MGI:3835446
• Gene: Parvb Location: Chr15:84116244-84199889 bp, + strand Genetic Position: Chr15, 39.78 cM, cytoband E3
• Alliance: Parvb^tm1Ref page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145476
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced part of exon 2 through exon 3 with a neomycin resistance cassette. (J:145476, J:327276)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Parvb Mutation: 52 strains or lines available

References

• Original: J:145476 Kruger M, et al., SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function. Cell. 2008 Jul 25;134(2):353-64
• All: 3 reference(s)