Gt(ROSA)26Sor^{tm1(GAP43/EGFP)Gld}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(GAP43/EGFP)Gld}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Martyn Goulding
• MGI ID: MGI:3835484
• Synonyms: R26^GAP43-EGFP, ROSA-GAP43-eGFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(GAP43/EGFP)Gld} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87771
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A floxed STOP cassette preceding a GAP43/EGFP fusion cDNA was inserted into the locus. Cre mediated removal of the STOP cassette is necessary for expression of the fusion gene in V1-derived neurons. (J:87771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:87771 Sapir T, et al., Pax6 and engrailed 1 regulate two distinct aspects of renshaw cell development. J Neurosci. 2004 Feb 4;24(5):1255-64
• All: 7 reference(s)