Tnip1^tm1.1Ama
Targeted Allele Detail

Summary

• Symbol: Tnip1^tm1.1Ama
• Name: TNFAIP3 interacting protein 1; targeted mutation 1.1, Averil Ma
• MGI ID: MGI:3835790
• Gene: Tnip1 Location: Chr11:54801611-54853743 bp, - strand Genetic Position: Chr11, 32.13 cM
• Alliance: Tnip1^tm1.1Ama page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145539
• Parent Cell Line: PRX-B6T (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exons 12 through 15. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts. (J:145539)

Expression

In Mice Carrying this Mutation:	360 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnip1 Mutation: 57 strains or lines available

References

• Original: J:145539 Oshima S, et al., ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development. Nature. 2009 Feb 12;457(7231):906-9
• All: 3 reference(s)