Tg(Slc6a3-cre/ERT2)1Span
Transgene Detail

Summary

• Symbol: Tg(Slc6a3-cre/ERT2)1Span
• Name: transgene insertion 1, Rainer Spanagel
• MGI ID: MGI:3835856
• Synonyms: DATCreERT2, Tg(Slc6a3-ERT2)1Span
• Transgene: Tg(Slc6a3-cre/ERT2)1Span Location: unknown
• Alliance: Tg(Slc6a3-cre/ERT2)1Span page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Slc6a3-cre/ERT2)1Span expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slc6a3 (MGI:94862)

• Mutation details: A cassette encoding a tamoxifen-inducible form of cre recombinase was knocked into the ATG start site of a murine Slc6a3 gene located on BAC RP24-243J21. The transgene was expressed in dopaminergic neurons in the brain. (J:139693)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a3 (mouse) Summary of all recombinase alleles driven by Slc6a3. Comparative matrix view of recombinase activities Alliance mouse Slc6a3 gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:139693 Engblom D, et al., Glutamate receptors on dopamine neurons control the persistence of cocaine seeking. Neuron. 2008 Aug 14;59(3):497-508
• All: 26 reference(s)