Kat14^{Gt(OST388291)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Kat14^{Gt(OST388291)Lex}
• Name: lysine acetyltransferase 14; gene trap OST388291, Lexicon Genetics
• MGI ID: MGI:3836392
• Synonyms: Atac2^-
• Gene: Kat14 Location: Chr2:144210952-144249595 bp, + strand Genetic Position: Chr2, 71.01 cM
• Alliance: Kat14^{Gt(OST388291)Lex} page

Mutation origin

• Mutant Cell Line: OST388291
• Germline Transmission: Earliest citation of germline transmission: J:145720
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector VICTR48, which contains a neo cassette, was inserted downstream of exon 3. The absence of protein was confirmed by western blot analysis on E9.5 embryo extracts. (J:145720)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST388291	CG644661 ; (MGI Seq Detail)	3' RACE	Chr2:144231091-144231275 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  6 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Kat14 Mutation: 75 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:145720 Guelman S, et al., The double-histone-acetyltransferase complex ATAC is essential for mammalian development. Mol Cell Biol. 2009 Mar;29(5):1176-88
• All: 2 reference(s)