Vtcn1^tm1Lpc
Targeted Allele Detail

Summary

• Symbol: Vtcn1^tm1Lpc
• Name: V-set domain containing T cell activation inhibitor 1; targeted mutation 1, Lieping Chen
• MGI ID: MGI:3836401
• Gene: Vtcn1 Location: Chr3:100732775-100804238 bp, + strand Genetic Position: Chr3, 43.78 cM
• Alliance: Vtcn1^tm1Lpc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145712
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 3 and 4 were replaced with a neo cassette. These exons encode IgV and IgC. (J:145712)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vtcn1 Mutation: 24 strains or lines available

References

• Original: J:145712 Zhu G, et al., B7-H4-deficient mice display augmented neutrophil-mediated innate immunity. Blood. 2009 Feb 19;113(8):1759-67
• All: 3 reference(s)