C2cd3^hty
Chemically induced Allele Detail

Summary

• Symbol: C2cd3^hty
• Name: C2 calcium-dependent domain containing 3; hearty
• MGI ID: MGI:3836402
• Synonyms: C2cd3^11A
• Gene: C2cd3 Location: Chr7:100021440-100119359 bp, + strand Genetic Position: Chr7, 54.35 cM
• Alliance: C2cd3^hty page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A mutation in the first nucleotide of the fourth intron, changing G to an A, disrupts splicing of the C2cd3 mRNA. RT-PCR using primers in the third and fifth exons of C2cd3 revealed multiple abnormal transcripts. No normal transcript are found by the RT-PCR analysis. (J:142506)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any C2cd3 Mutation: 101 strains or lines available

References

• Original: J:101649 Zohn IE, et al., Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse. Birth Defects Res A Clin Mol Teratol. 2005 Sep;73(9):583-90
• All: 2 reference(s)