Tg(IGH-Btk)1Witt
Transgene Detail

Summary

• Symbol: Tg(IGH-Btk)1Witt
• Name: transgene insertion 1, Owen N Witte
• MGI ID: MGI:3836559
• Transgene: Tg(IGH-Btk)1Witt Location: unknown
• Alliance: Tg(IGH-Btk)1Witt page

Transgene origin

• Strain of Origin: C57BL/6 x C3H

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(IGH-Btk)1Witt expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Btk (MGI:88216)

• Mutation details: This transgene consists of the murine H chain Ig enhancer and the human H chain Ig promoter driving expression of a murine Btk cDNA. (J:108696)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:108696 Satterthwaite AB, et al., Btk dosage determines sensitivity to B cell antigen receptor cross-linking. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13152-7
• All: 2 reference(s)