Neto1^tm1Mci
Targeted Allele Detail

Summary

• Symbol: Neto1^tm1Mci
• Name: neuropilin (NRP) and tolloid (TLL)-like 1; targeted mutation 1, Roderick R McInnes
• MGI ID: MGI:3836584
• Synonyms: Neto1^tlz
• Gene: Neto1 Location: Chr18:86413077-86524843 bp, + strand Genetic Position: Chr18, 58.47 cM
• Alliance: Neto1^tm1Mci page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145953
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Mutation details: Exon 2 and 3 were replaced with a tau-lacZ (tlz) and floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:145953)

Generation of the Neto1^tm1Mci allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Neto1 Mutation: 42 strains or lines available

References

• Original: J:145953 Ng D, et al., Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol. 2009 Feb 24;7(2):e41
• All: 9 reference(s)