Tg(PER2*S662G)867Ljp
Transgene Detail

Summary

• Symbol: Tg(PER2*S662G)867Ljp
• Name: transgene insertion 867, Louis J Ptacek
• MGI ID: MGI:3837437
• Transgene: Tg(PER2*S662G)867Ljp Location: unknown
• Alliance: Tg(PER2*S662G)867Ljp page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(PER2*S662G)867Ljp expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PER2 (8864)

  Per2	(MGI:1195265)

• Mutation details: A human BAC clone was used as the transgene vector. An A to G transition was engineered into the BAC to change the AGT serine codon for amino acid residue 662 to a GGT glycine codon. (J:126404)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:126404 Xu Y, et al., Modeling of a human circadian mutation yields insights into clock regulation by PER2. Cell. 2007 Jan 12;128(1):59-70
• All: 1 reference(s)