Tg(Pvalb-cre)1Tama
Transgene Detail

Summary

• Symbol: Tg(Pvalb-cre)1Tama
• Name: transgene insertion 1, Nobuaki Tamamaki
• MGI ID: MGI:3837553
• Synonyms: PV-cre
• Transgene: Tg(Pvalb-cre)1Tama Location: unknown
• Alliance: Tg(Pvalb-cre)1Tama page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pvalb-cre)1Tama expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pvalb (MGI:97821)

• Mutation details: A cre recombinase gene was inserted into the ATG start site of a murine Pvalb gene located on a BAC. The targeted BAC was inserted into zygotes and four founder lines were generated. This line was chosen for further propagation based on colocalization of cre recombinase and endogenous Pvalb. Cre expression was detected in select neurons of the neocortex, cingurate cortex, pyriform cortex, hippocampus, basal ganglia, and the reticular thalamic nucleus region of the brain. (J:146140)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pvalb (mouse) Summary of all recombinase alleles driven by Pvalb. Comparative matrix view of recombinase activities Alliance mouse Pvalb gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:146140 Tanahira C, et al., Parvalbumin neurons in the forebrain as revealed by parvalbumin-Cre transgenic mice. Neurosci Res. 2009 Mar;63(3):213-23
• All: 12 reference(s)