Csnk1d^{Gt(TEA020)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Csnk1d^{Gt(TEA020)Byg}
• Name: casein kinase 1, delta; gene trap TEA020, BayGenomics
• MGI ID: MGI:3837651
• Synonyms: Csnk1delta^-
• Gene: Csnk1d Location: Chr11:120849816-120882156 bp, - strand Genetic Position: Chr11, 84.75 cM, cytoband E2
• Alliance: Csnk1d^{Gt(TEA020)Byg} page

Mutation origin

• Mutant Cell Line: TEA020
• Germline Transmission: Earliest citation of germline transmission: J:97658
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: A promoterless beta-geo cassette inserted between exon 4 and 5 of the gene. A fusion transcript was expressed that contains exons upstream of the insertion joined to the beta-geo gene. This is considered a null allele. (J:97658)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  TEA020	CC325521 ; (MGI Seq Detail)	5' RACE	Chr11:120863792-120881882 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  8 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Csnk1d Mutation: 15 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:97658 Xu Y, et al., Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome. Nature. 2005 Mar 31;434(7033):640-4
• All: 4 reference(s)