Tg(Mc2r-Arntl)1Kyki
Transgene Detail

Summary

• Symbol: Tg(Mc2r-Arntl)1Kyki
• Name: transgene insertion 1, Kyungjin Kim
• MGI ID: MGI:3837662
• Synonyms: MC2R-AS-BMAL1
• Transgene: Tg(Mc2r-Arntl)1Kyki Location: unknown
• Alliance: Tg(Mc2r-Arntl)1Kyki page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The mouse promoter was used to drive adrenal-specific expression of an anti-sense version of part of the open reading frame. Tissue specific knock-down of endogenous gene expression was confirmed by RT-PCR in the adrenal gland. However, expression is normal in the suprachiasmatic nuclei-anterior hypothalamus, liver, kidney, and pancreas. No line information was given, but the line presented has 60 copies of the transgene. (J:146305)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:146305 Son GH, et al., Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20970-5
• All: 1 reference(s)