Il10ra^m1Jskg
Chemically induced Allele Detail

Summary

• Symbol: Il10ra^m1Jskg
• Name: interleukin 10 receptor, alpha; mutation 1, Jonsoo Kang
• MGI ID: MGI:3838223
• Synonyms: Il10ra^N
• Gene: Il10ra Location: Chr9:45165135-45180447 bp, - strand Genetic Position: Chr9, 24.84 cM
• Alliance: Il10ra^m1Jskg page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: ENU mutagenesis caused a single base mutation that resulted in a stop codon at amino acid 220. This is considered a null allele. (J:146644)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il10ra Mutation: 32 strains or lines available

References

• Original: J:146644 Friedline RH, et al., CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance. J Exp Med. 2009 Feb 16;206(2):421-34
• All: 1 reference(s)