Eri1^tm1.2Anse
Targeted Allele Detail

Summary

• Symbol: Eri1^tm1.2Anse
• Name: exoribonuclease 1; targeted mutation 1.2, K Mark Ansel
• MGI ID: MGI:3838637
• Gene: Eri1 Location: Chr8:35932419-35962687 bp, - strand Genetic Position: Chr8, 21.16 cM, cytoband B1.1
• Alliance: Eri1^tm1.2Anse page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146701
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombiantion was used to remove exon 3. The absence of protein expression was confirmed by western blot analysis on several tissues. (J:146701)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eri1 Mutation: 19 strains or lines available

References

• Original: J:146701 Ansel KM, et al., Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing. Nat Struct Mol Biol. 2008 May;15(5):523-30
• All: 2 reference(s)