Epb41l1^tm1.1Aliv
Targeted Allele Detail

Summary

• Symbol: Epb41l1^tm1.1Aliv
• Name: erythrocyte membrane protein band 4.1 like 1; targeted mutation 1.1, Aleksandra Ivanovic
• MGI ID: MGI:3838872
• Synonyms: 4.1N^-
• Gene: Epb41l1 Location: Chr2:156262829-156385134 bp, + strand Genetic Position: Chr2, 77.39 cM
• Alliance: Epb41l1^tm1.1Aliv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146603
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exon 2. Western blot analysis confirmed a 70% reduced expression of two short isoforms. (J:146603)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epb41l1 Mutation: 165 strains or lines available

References

• Original: J:146603 Wozny C, et al., The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression. J Cell Sci. 2009 Mar 1;122(Pt 5):735-44
• All: 1 reference(s)