Raly^{Gt(RST374)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Raly^{Gt(RST374)Byg}
• Name: hnRNP-associated with lethal yellow; gene trap RST374, BayGenomics
• MGI ID: MGI:3838882
• Synonyms: Raly^Trap
• Gene: Raly Location: Chr2:154633016-154709181 bp, + strand Genetic Position: Chr2, 76.83 cM
• Alliance: Raly^{Gt(RST374)Byg} page

Mutation origin

• Mutant Cell Line: RST374
• Germline Transmission: Earliest citation of germline transmission: J:146879
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1TMpfs
• Mutation details: The gene trap vector inserted into intron 2. Reduced transcript expression was confirmed by quantitative RT-PCR on liver, testes, and spleen extracts. (J:146879)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RST374	CC183646 ; (MGI Seq Detail)	5' RACE	Chr2:154662925-154663007 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Raly Mutation: 56 strains or lines available

References

• Original: J:146879 Heaney JD, et al., Deletion of eIF2beta suppresses testicular cancer incidence and causes recessive lethality in agouti-yellow mice. Hum Mol Genet. 2009 Apr 15;18(8):1395-404
• All: 2 reference(s)