Ptprh^tm1.1Mato
Targeted Allele Detail

Summary

• Symbol: Ptprh^tm1.1Mato
• Name: protein tyrosine phosphatase receptor type H; targeted mutation 1.1, Takashi Matozaki
• MGI ID: MGI:3839028
• Synonyms: Sap1^-
• Gene: Ptprh Location: Chr7:4551611-4607040 bp, - strand Genetic Position: Chr7, 2.63 cM
• Alliance: Ptprh^tm1.1Mato page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146871
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exons 17 and 18. The absence of protein expression was confirmed by western blot analysis on ileum extracts. (J:146871)

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ptprh Mutation: 60 strains or lines available

References

• Original: J:146871 Sadakata H, et al., SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis. Genes Cells. 2009 Mar;14(3):295-308
• All: 2 reference(s)