Hprt1^{tm3(APOA5)Lap}
Targeted Allele Detail

Summary

• Symbol: Hprt1^{tm3(APOA5)Lap}
• Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 3, Len A Pennacchio
• MGI ID: MGI:3839280
• Synonyms: APOA5*4
• Gene: Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
• Alliance: Hprt1^{tm3(APOA5)Lap} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145098
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Hprt1^{tm3(APOA5)Lap} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  APOA5 (116519)

  Apoa5

  (MGI:1913363)

• Haplotype 4 of the human gene was knocked into the 5' untranslated region of the locus. (J:145098)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hprt1 Mutation: 1279 strains or lines available

References

• Original: J:145098 Ahituv N, et al., In vivo characterization of human APOA5 haplotypes. Genomics. 2007 Dec;90(6):674-9
• All: 1 reference(s)